Introduction Meshashringi is popularly known as 'Gudmar' in Hindi which means 'sugar destroyer'.Meshashringi helps regulate sugar levels by promoting the secretion of insulin, regenerating pancreatic cells and increasing the activities of enzymes responsible for healthy glucose utilization.Gurmar (Gudmar) is effective in managing Type II diabetes due to its antioxidant and anti-inflammatory properties. It prevents the pancreatic cells against damage caused by free radicals and increases insulin secretion thereby lowers the blood sugar level.Meshashringi, commonly known as Periploca of the woods is a large woody climber vine seen through out India. The fruits of the plant resembles that of horns of